What's the greater risk - to tolerate some health problems or cure them at the expense of creating other health issues which might end up being a lot worse?
THOUSANDS of Australians could be taken off cholesterol-lowering medications because of mounting evidence they increase the risk of diabetes and dementia.
Australian health authorities are reviewing their advice after US regulators announced statins will now carry warnings they could increase the risk of diabetes and cognitive impairment.
Statins are the most commonly prescribed drugs in Australia, with about 2 million people thought to be taking them to reduce their heart disease risk.
The president of the Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, David Le Couteur, said Australia had one of the highest rates of statin use in the world, and people who were not at high risk of heart disease needed to reconsider using them.
He said doctors and other health practitioners should focus on lifestyle interventions for people with high cholesterol but without other risks such as previous heart attacks, high blood pressure and smoking.
Despite statins being linked to diabetes, he said people with the condition should still use them as diabetes itself put them at risk of heart disease. "If you have diabetes that's even more reason to be on statins," he said.
Statins have long been touted as a miracle drug, with some doctors and researchers pushing for their use in all older people. But Professor Le Couteur said that was unwise. "Unfortunately the history of medicine is chequered with hopes that have turned out to be dashed and even caused harm," he said.
The evidence showing a link with cognitive impairment was not as strong as the links with diabetes, but if a patient developed symptoms he would consider taking them off the drugs.
But the director of the Baker IDI Heart and Diabetes Institute, Garry Jennings, said people should not stop taking statins.
"I hope that pretty much everyone who is on a statin in Australia is on it for a very good reason, although there might be a few lower-risk people on the fringe," he said. "Statins work and there have been tens of thousands of people in trials … the overall benefit is clear.''
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