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........... it is hard not to be excited about these findings and the existence of three safe and efficacious COVID-19 vaccines, with a further 55 already in clinical trials.1 With a range of manufacturers, a very large global investment in production, and cooperation in procurement and distribution, it seems likely that 2021 will see COVID-19 vaccines made available to all countries in the world—at least for their priority groups.9 Perhaps by this time next year, we can celebrate the global control of SARS-CoV-2, in person. ........................

https://www.thelancet.com/journals/lanc ... 4/fulltext

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............ No COVID-19-related hospital admissions occurred in ChAdOx1 nCoV-19 recipients, whereas ten (two of which were severe) occurred in the control groups. ..................

https://www.thelancet.com/journals/lanc ... 4/fulltext

'The Control Group' means the group who had a fake vaccine as opposed to those who had a real vaccine.

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........... what vaccine reactions are normal, and what side effects are possible?

Normal vaccination reactions
It is normal to have certain reactions after a vaccination: There may be redness, swelling or pain around the injection site. Fatigue, fever, headache and aching limbs are also not uncommon in the first three days after vaccination.

These normal vaccine reactions are usually mild and subside after a few days. They show that the vaccine is working, because it stimulates the immune system and the body forms antibodies against the infection that is only "feigned" by the vaccination.
Typical vaccine reactions are mild and disappear after a few days

Accordingly, such typical vaccination reactions have also been reported after receiving the BioNTech-Pfizer, Moderna, AstraZeneca and the Russian Sputnik V vaccines, which are already in use.

Rarely serious side effects
In addition to the typical vaccination reactions, there were also individual cases of sometimes severe side effects after vaccination, such as allergic shocks, which were reported in detail. But these are isolated cases.

Overall, the approved vaccines are safe, according to the European Medicines Agency (EMA), the US Food and Drug Administration (FDA) and the World Health Organization (WHO); otherwise, they would not have authorized the vaccines.

Some of the new vaccines — so-called mRNA vaccines — are different from the established vaccines: they do not contain weakened or killed viruses. Instead they contain only a blueprint for a component of the COVID-19 pathogen.

Others are so-called vector vaccines that use harmless adenoviruses (such as cold viruses that only affect chimpanzees) as transporters to introduce the surface protein of SARS-CoV-2, the spike protein, and thereby trigger the immune response.

Here is an overview of the risks and side effects of the commonly mentioned vaccines:

The Biontech-Pfizer vaccine
During the approval phase, no serious side effects occurred with the BNT162b2 vaccine developed by companies BioNTech of Germany and Pfizer of the US. The typical vaccination reactions such as fatigue and headache were less frequent and weaker in older patients.

However, since this mRNA vaccine has been in use, a few patients had a severe allergic reaction immediately after the injection. One patient in the USA and two Britons even went into anaphylactic shock, associated with reddening of the skin and shortness of breath.

Since these individuals either had no previous illnesses or were not known to be allergic to certain vaccine ingredients, the British Medicines and Healthcare products Regulatory Agency ( MHRA ) warned in particular people who are allergic to certain vaccine ingredients, or have already suffered an anaphylactic shock, against getting the vaccination.

The manufacturers do not see any direct connection to the vaccination in the case of a US physician with no previous illnesses who died from a brain hemorrhage due to immune thrombocytopenia 16 days after receiving the vaccination. This occurs when the immune system reduces the number of platelets.

Headlines were made when 33 people in Norway died a few days after the first vaccination, all of whom were more than 75 years old and had severe underlying diseases. While manufacturers are still investigating the causes, the Norwegian Health Authority has changed its instructions for vaccinating older, frail people against COVID-19. In the future, doctors are to decide individually whether the benefits of vaccination outweigh the risks of side effects.

The Moderna vaccine
The mRNA-1273 vaccine from US company Moderna is also a gene-based vaccine that is very similar in principle to the one from BioNTech/Pfizer.

During the clinical trials, participants tolerated the vaccine well, according to the manufacturer and testing authorities. The usual vaccination reactions were only mild or moderate and didn't last long. However, almost 10% of those vaccinated with mRNA-1273 experienced fatigue, according to an interim report by an independent surveillance panel.

The mRNA-1273 vaccine from the US company Moderna is similar in principle to the one from BioNTech/Pfizer

Severe allergic reactions to the Moderna vaccine are "rare," according to the US Centers for Disease Control and Prevention (CDC). The CDC is basing that assessment on the documentation of 4,041,396 doses of the vaccine that were administered between December 21, 2020 and January 10, 2021. A total of 108 allergic reactions were recorded, but only 10 recipients went into anaphylactic shock. The CDC reported that none of the allergic reactions led to death.

A very small number of people who received the Moderna vaccine experienced facial nerve paralysis. However, it is still unclear whether these reactions are actually related to the core ingredient of the vaccine. It is possible that the side effects were not triggered by the mRNA, but by lipid nanoparticles that serve as carriers for the mRNA and are later broken down by the body.

Isolated cases of facial paralysis, mostly temporary, occurred sporadically during the clinical trials of the BioNTech/Pfizer and Moderna vaccines, but also during ongoing vaccinations in Israel.

The AstraZeneca vaccine
At the British-Swedish company AstraZeneca, an incident during clinical trials in September caused a stir because one person suffered inflammation of the spinal cord after vaccination. The trial was briefly halted until an independent panel of experts determined that the inflammation was probably not related to the vaccination.

A medical syringe is seen with the AstraZeneca company logo displayed on a screen in the background
AstraZeneca's vaccine has not yet been approved in the EU

Otherwise, only typical vaccination reactions such as pain at the injection site, muscle pain, headache and fatigue occurred with the vaccine from AstraZeneca. Again, vaccine reactions were less frequent and milder in older people. This is a vector vaccine. ................

https://www.dw.com/en/covid-19-risks-an ... a-56136620

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Almost 200,000,000 covid shots given worldwide.

Amazing, great stuff.